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Concurrent Assessment of the Antinociceptive and Behaviorally Disruptive Effects of Opioids in Squirrel Monkeys

Opioid analgesics, which remain the primary treatment for moderate to severe pain, can exert other effects, such as sedation or reduced consciousness, that impair behavior and, depending on the circumstance, may thereby constrain their therapeutic utility.5 In some instances (eg, postoperative recovery), behavioral impairment may not be a problem and, indeed, opioid-induced sedation may be somewhat desirable. However, sedative effects may limit medication compliance in certain patient populations and, generally, are undesirable in the workplace and other non-hospital settings.

Concurrent Assessment of the Antinociceptive and Behaviorally Disruptive Effects of Opioids in Squirrel Monkeys

Orginally Published At: Pain Journal

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