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Disease-Related Microstructural Differences in the Brain in Women With Provoked Vestibulodynia

Provoked vestibulodynia (PVD) is a chronic pelvic pain disorder affecting approximately 16% of women,37 with a significant effect on quality of life.37 Individuals with PVD report localized hypersensitivity and severe pain of the vulvar vestibule upon vaginal penetration (eg, intercourse, tampon use) in the absence of detectable infection or inflammatory etiology.4,31 The underlying pathophysiology of PVD is largely unknown, and treatment options remain unsatisfactory.85 Available evidence suggests that peripheral as well as central alterations in sensory processing appear to be involved.

Disease-Related Microstructural Differences in the Brain in Women With Provoked Vestibulodynia

Orginally Published At: Pain Journal

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