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Endogenous pain modulation profiles among individuals with chronic pain: Relation to opioid use

It is well known that nociceptive signals can be modulated by central pain inhibitory and facilitatory processes 1,8,82. These pain-modulatory processes operate at various levels of the central nervous system and are assumed to play a determining role in the manifestations of chronic pain and in shaping inter-individual variability in the trajectory of many persistent pain conditions 6,25,51,83. Considerable studies have been conducted using quantitative sensory testing (QST) to assess pain inhibition and pain facilitation 9,19,71.

Endogenous pain modulation profiles among individuals with chronic pain: Relation to opioid use

Orginally Published At: Pain Journal

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