Watched this days ago and it keeps haunting me… that young woman’s poor arm, red and blotchy, with “do not touch” written on it. What a weird “blessing” to have chronic pain that is so severe it has a visible effect. (Visible problems get taken seriously. Invisible pain often does not, tragically.) I’ve gotten quite […]
An excerpt from my transcutaneous electrical stimulation (TENS) article, describing an important basic principle that explains why so many people “swear by” so many different kinds of treatment methods: Pain is completely controlled by an overprotective brain that likes to sound the alarm too loudly, too often, regardless of what’s actually going on in tissues. […]
Women disproportionately suffer from chronic pain conditions including irritable bowel syndrome (IBS), fibromyalgia, migraine, and temporomandibular joint pain, many of which are comorbid with anxiety or depression disorders.7,9,11,29,37,110 During the past decades, efforts have been made to explore the mechanisms underlying sex differences in stress-induced anxiety and depression (for review, see Bangasser and Valentino8 and […]
Last week on Twitter I promoted the “new organ” story much too uncritically, because it seemed neat and I was in a hurry: Seemingly solid layers of connective tissue turn out to be chock-a-block with a previously unknown but extensive system of lymphatic “spaces.” Many implications for pathology. How was this missed? It’s wrecked by […]
Chronic pain experienced by patients with pachyonychia congenita may be caused by damage to the peripheral nerve fibers, with the hyperalgesia and allodynia observed in affected regions likely to be manifestations of peripheral sensitization.
Chronic Pain in Pachyonychia Congenita May Have Neuropathic Origin
Orginally Published At: Neuropathic Pain