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Intrinsic Activity of C57BL/6 Substrains Associates with High-Fat Diet-Induced Mechanical Sensitivity in Mice

Obesity and metabolic syndrome are increasing in an alarming fashion worldwide, and increasing attention is being paid to the strong relationship between obesity, metabolic syndrome and pain19. This growing correlation of obesity and pain has been investigated using numerous animal models, many utilizing differing strains of animals, diets, and obesity phenotypes, and it’s clear that the genetic component underlying pain is a key contributor. Animal studies have identified important differences in pain associated with different strains of rodents20.

Intrinsic Activity of C57BL/6 Substrains Associates with High-Fat Diet-Induced Mechanical Sensitivity in Mice

Orginally Published At: Pain Journal

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