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Pain Adaptability in Individuals With Chronic Musculoskeletal Pain Is Not Associated With Conditioned Pain Modulation

The ability of the body to modulate pain without the help of medical interventions is known as endogenous pain inhibition. Conditioned pain modulation (CPM) is one of the well studied endogenous pain inhibitions. It involves the reduction of pain from a painful stimulus when a second painful stimulus is applied distantly or heterotopically.63 Potency of CPM is defined by percentage change in pain threshold or pain rating at baseline to that during or after cold pressor. However, the relationship between potency of CPM and chronic pain is inconclusive; some studies showed that patients with high intensity of chronic pain displayed poorer CPM4,17 whereas other studies showed no association between pain intensity and potency of CPM.

Pain Adaptability in Individuals With Chronic Musculoskeletal Pain Is Not Associated With Conditioned Pain Modulation

Orginally Published At: Pain Journal

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