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Pain After Spinal Cord Injury Is Associated With Abnormal Presynaptic Inhibition in the Posterior Nucleus of the Thalamus

Chronic pain is one of the most debilitating disorders associated with spinal cord injury (SCI) and is estimated to affect up to 80% of all patients with SCI.33,81 Such central pain after SCI (SCI-Pain) typically presents as constant, diffuse, and bilateral pain commonly described as shooting, stabbing, or burning,17,19,98 and is generally refractory to treatment by conventional therapies.6,21,33,74,91 Thus, there is a critical need for the development of more efficacious therapeutics to ameliorate this crippling condition.

Pain After Spinal Cord Injury Is Associated With Abnormal Presynaptic Inhibition in the Posterior Nucleus of the Thalamus

Orginally Published At: Pain Journal

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