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The relationship of endocannabinoidome lipid mediators with pain and psychological stress in women with fibromyalgia – a case control study

Fibromyalgia (FM) is a heterogeneous and complex syndrome manifested as generalized hyperalgesia and chronic widespread musculoskeletal pain (CWP). Common symptoms of FM also include, stiffness, fatigue, sleep disturbances, and cognitive dysfunction1 and common co-morbidities include depression, anxiety, and stress.2 The prevalence of FM is 2-4%,3,4 peaks around 55-65 years of age, and shows a strong female predominance.5 FM results in physical and psychological distress, reduced quality of life, increased use of health resources, and loss of work productivity.

The relationship of endocannabinoidome lipid mediators with pain and psychological stress in women with fibromyalgia – a case control study

Orginally Published At: Pain Journal

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